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Project Information

Project Information


Understanding the Role of the Immune System in Improving Tissue Regeneration: A Workshop


Project Scope:

The Forum on Regenerative Medicine will hold a one-day public workshop to explore potential promising approaches to modulate the immune system and/or the regenerative medicine product for improving the clinical outcomes of tissue repair and regeneration in patients.

Workshop discussions may examine:

  • lessons learned from other fields (e.g. organ or bone marrow transplantation) about the role of the host’s immune system in accepting a graft to inform whether manipulation of a graft can impact the acceptance or rejection of it;
  • topics such as potential approaches for modulating critical immune system pathways and communication mechanisms between the immune system and damaged and/or diseased tissues;
  • the application of these lessons learned to the development and use of regenerative medicine products, for example:
o what immune factors and pathways play a role in regeneration;
o biomarkers that may be useful for assessing a patient’s immune status or response to regenerative medicine therapies; 
o scaffolds, biomaterials, and other bioengineering tools that may modify immune responses; and 
o imaging technologies to leverage immune surveillance in patients and evaluation of the results of regenerative therapies. 

A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize the workshop, select and invite speakers and discussants, and moderate the discussions. Proceedings of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Status: Current

PIN: HMD-HSP-21-03

RSO: Beachy, Sarah

Board(s)/Committee(s):

Board on Health Sciences Policy

Topic(s):

Health and Medicine
Policy for Science and Technology


Parent Project(s): N/A


Child Project(s): N/A



Geographic Focus:

Committee Membership


Nadya Lumelsky - (Co-Chair)
Kimberlee Potter - (Co-Chair)
Steven Becker
Jennifer H. Elisseeff
Sadik Kassim
Candace Kerr
Cato T. Laurencin
Richard H. McFarland
Rachel Salzman
Sohel Talib
Daniel Weiss

Events


Event Type :  
Workshop

Description :   

The Forum on Regenerative Medicine will host a two-day workshop to explore potential promising approaches to modulate the immune system and/or the regenerative medicine product for improving the clinical outcomes of tissue repair and regeneration in patients. Discussions at the workshop may explore the current state of knowledge about immune tolerance mechanisms and lessons learned from other areas of research; advances in engineering of allogeneic donor cells for acceptance by the host's immune system; effects of aging and other factors on the local environment, endogenous repair, and wound healing; modulating the host immune system to create a pro-regenerative environment; and developing tools and preclinical models for monitoring and optimizing the host's pro-regenerative environment.

Note: the workshop will be streaming on this page on both days of the workshop.



Registration for in Person Attendance :   
N/A


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Sarah Beachy
Contact Email:  RegenMed@nas.edu
Contact Phone:  -

Agenda
-
Supporting File(s)
-
Is it a Closed Session Event?
No

Publication(s) resulting from the event:

-

Publications

Publications

No data present.