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Project Information

Project Information

Advancing Diagnostic Excellence: A Workshop Series

Project Scope:

At the request of the Gordon and Betty Moore Foundation, the National Academies of Science, Engineering, and Medicine will conduct a series of three one day workshops to examine the current scientific landscape and research opportunities for improving diagnosis within the U.S. health care system. Each workshop will focus on a different priority category of disease associated with a disproportionate share of diagnostic error and patient harm. The workshops will focus on:

  1. Acute cardiovascular events,
  2. Infections (particularly hospital-related infections), and
  3. Selected cancers.
Workshop participants will consider strategies to reduce patient harm from diagnostic errors in the selected disease categories. Presentations and discussions will also emphasize initiatives used to lower costs and redundancies in the diagnostic process, while improving health outcomes. Critical components include development and validation of measurement approaches to strengthen accountability for diagnostic performance.

In consultation with sponsor staff, three planning committees will be established to develop workshop agendas, invite speakers, and discuss data and information relevant to clinical practices, published studies, and new developments in the field of diagnostic excellence. Some planning committee members will be selected to participate in the planning of all 3 workshops, for continuity across workshops. Agenda topics may include:
  • new technologies,
  • innovations using artificial intelligence,
  • machine- and crowd-learning strategies for assessing patient safety,
  • quality improvement, and
  • accountability related to diagnostic errors.
For cancer-related activities, the workshop could be conducted in collaboration with the National Cancer Policy Forum at the National Academies.

In accordance with institutional guidelines, a designated rapporteur will prepare proceedings of each workshop based on the presentations and discussion during that workshop. The proceedings will be subject to the National Academies review procedures prior to release.

Status: Current

PIN: HMD-HCS-20-02

RSO: Zevon, Emily


Board on Health Care Services


Health and Medicine

Geographic Focus:

Committee Membership

Andrew B. Bindman - (Chair)
Andrew Bindman, MD (Chair), is a Professor of Medicine, Epidemiology & Biostatistics, and a core faculty member within the Philip R. Lee Institute for Health Policy Studies at the University of California, San Francisco. He is a primary care physician with federal and state health policy experience who has practiced and taught clinical medicine at Zuckerberg San Francisco General Hospital for over 30 years while also conducting health services research to improve access to high quality health care. Dr. Bindman is a leading national voice on primary care, the health care safety net, and population health. He was appointed as the Director for the Agency for Healthcare Research and Quality (AHRQ) within the US Department of Health and Human Services in 2016 and he served in that role until the end of the Obama administration. He currently serves as the co-editor in chief of the journal, Health Services Research. Dr. Bindman was elected to the National Academy of Medicine in 2015.
Derek C. Angus
Derek C. Angus, MD, MPH, FRCP, FCCM, FCCP, is Chair of the Department of Critical Care Medicine of both the University of Pittsburgh School of Medicine and the UPMC Healthcare System. At the University, he holds the rank of Distinguished Professor and the Mitchell P. Fink Endowed Chair in Critical Care Medicine with secondary appointments in Medicine, Health Policy and Management, and Clinical and Translational Science and he directs the CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illnesses) Center. He also co-directs the UPMC ICU Service Center, responsible for the provision of ICU services across the 20-plus hospital system.

Upon completing his undergraduate studies at the University of Glasgow School of Medicine, Glasgow, United Kingdom, Dr. Angus completed his intern and residency training at the Western Infirmary and the Southern General Hospital in Glasgow. He then traveled to the U.S. and obtained his MPH from the University of Pittsburgh Graduate School of Public Health. During this time he was a Fellow of Critical Care Medicine, a Research Fellow, and a Research Fellow in Disaster and Emergency Medicine at the University of Pittsburgh.

Dr. Angus’ research interests include clinical, epidemiologic, and translational studies of sepsis, pneumonia, and multisystem organ failure and health services research of the organization and delivery of critical care services. Dr. Angus has led several large NIH-funded multicenter studies in the critically ill, the most recent of which is ProCESS (Protocolized Care for Early Septic Shock), a 40-center study focusing on how to best provide early resuscitation for septic shock. Dr. Angus has published several hundred papers, reviews and book chapters, and is currently section editor for “Caring for the Critically Ill” for JAMA. He is the recipient of numerous awards, including the Presidential Citation Award of the Society of Critical Care Medicine (1999, 2004-2006, 2008, 2011, 2013), the Master of Critical Care Medicine from the American College of Critical Care Medicine (2012), Best Doctors of America (2005-present), and the Best Doctors in Pittsburgh (2012-present), Top 10 Outstanding Clinical Research Achievements from the Clinical Research Forum (2015), and an Honorary Member of the European Society of Intensive Care Medicine (2015). Dr. Angus is a member of the Society of Critical Care Medicine, the American College of Chest Physicians, the American Thoracic Society, the Association for Health Services Research, the European Society of Intensive Care Medicine, and the American College of Critical Care Medicine.

Pascale Carayon
Pascale Carayon, MD, PhD, is the Leon and Elizabeth Janssen Professor in Engineering, Director of the Center for Quality and Productivity Improvement, Founding Director of the Wisconsin Institute for Healthcare Systems Engineering and leader of the interdisciplinary Systems Engineering Initiative for Patient Safety at the University of Wisconsin-Madison, USA. She received her Engineer diploma from the Ecole Centrale de Paris, France, and her PhD in Industrial Engineering from the University of Wisconsin-Madison. She has three decades of research experience analyzing, designing and improving complex work systems such as those in healthcare. In the last 20 years, her research has focused on patient safety and healthcare issues such as design of health information technologies. As an industrial and systems engineer, she is renowned for her groundbreaking contributions in modeling complex system interactions in healthcare processes that influence patient safety and other outcomes for patients and healthcare professionals. She is a Fellow of the Human Factors and Ergonomics Society and Fellow of the International Ergonomics Association. In 2016, she received the John M. Eisenberg Patient Safety and Quality Award for Individual Achievement. Since 2015, Becker’s Hospital Review has selected her yearly as one of 50 experts leading the field of patient safety.
Gari Clifford
Gari Clifford, DPhil, is a tenured Professor of Biomedical Informatics and Biomedical Engineering at Emory University and the Georgia Institute of Technology, and the Chair of the Department of Biomedical Informatics (BMI) at Emory. His research focuses on the application of signal processing and machine learning to medicine to classify, track and predict health and illness. His focus research areas include critical care, digital psychiatry, global health, mHealth, neuroinformatics and perinatal health. After training in Theoretical Physics, he transitioned to AI and Engineering for his doctorate (DPhil) at the University of Oxford in the 1990’s. He subsequently joined MIT as a postdoctoral fellow, then Principal Research Scientist where he managed the creation of the MIMIC II database, the largest open access critical care database in the world. He later returned as an Associate Professor of Biomedical Engineering to Oxford, where he helped found its Sleep & Circadian Neuroscience Institute and served as Director of the Centre for Doctoral Training in Healthcare Innovation at the Oxford Institute of Biomedical Engineering. As Chair, Dr Clifford has established BMI as a leading center for critical care and mHealth informatics, and as a champion for open access data and open source software in medicine, particularly through his leadership of the PhysioNet/CinC Challenges and contributions to the PhysioNet Resource. Despite this, he is a strong supporter of commercial translation, working closely with industry, and serves as CTO of MindChild Medical, a spin out from his research at MIT.
Laura Evans
Laura Evans, MD, MSc is the Associate Professor in the Division of Pulmonary, Critical Care and Sleep Medicine at the University of Washington and Medical Director of Critical Care at the University of Washington Medical Center. Previously, Dr. Evans was an associate professor of medicine at New York University School of Medicine and the Medical Director of Critical Care at Bellevue Hospital. She was also serves as the associate program director for the NYU Pulmonary and Critical Care Fellowship Program. Her interests focus on education, patient safety and quality improvement in the intensive care unit. Dr Evans earned her medical degree at the University of Michigan and did her residency in internal medicine at Columbia University. She completed pulmonary and critical care medicine fellowship training and earned a Master of Science in epidemiology at the University of Washington. She joined the faculty of NYU and Bellevue Hospital in 2006. In her role there, she led the evacuation of the Bellevue Hospital intensive care units in the aftermath of Hurricane Sandy and was the clinical lead for New York City’s only patient with Ebola. She joined the steering committee of the Surviving Sepsis Campaign in 2012 and is the current Surviving Sepsis Campaign guidelines co-chair. She also serves on the Council of the Society of Critical Care Medicine.
Kathryn M. McDonald
Kathryn McDonald, PhD, is an international thought leader who focuses on bringing an evidence-based, patient-centered approach to the study of health care delivery. She explores what makes for safe, affordable, and high-quality health care delivery systems and the factors that prevent health organizations from achieving this standard of care.McDonald develops tools for measuring patient safety and quality that are used by private and public care providers alike. McDonald created a set of standardized health care quality measurements called Quality Indicators, which are used to analyze administrative data from hospitals—including Johns Hopkins—to identify potential quality concerns and track changes over time. She is currently working on an ongoing study that examines the ways that a patient’s age, race, and sex may contribute to errors in medical diagnoses and disparities in patient outcomes. McDonald hopes to understand how “visible factors” put young people, women, and African American people at risk for misdiagnoses of infections, cancer, and cardiovascular issues.
Lyle L. Moldawer
Lyle Moldawer, PhD, received his PhD in Experimental Medicine in 1986 from the Gothenburg University in Sweden. For the past 30 years, he has conducted inflammation research testing key hypotheses that explore the inflammatory response to trauma and sepsis. Funded continuously by the National Institute of Health (NIH) for over 25 years, Dr Moldawer is a past NIH MERIT Award recipient. His current research at the University of Florida focuses on populations at the highest risk of developing sepsis, the very young (premature infants) and the very old. He has published over 400 peer-reviewed publications and has been cited more than 28,000 times.
Saul Weingart
Saul N. Weingart, MD, PhD is the Chief Medical Officer and SVP of Medical Affairs at Tufts Medical Center and Professor of Medicine, Public Health, and Community Medicine at Tufts University School of Medicine. Weingart is a leader in the movement to measure and improve quality. His research addresses patient engagement in patient safety, patient safety in ambulatory specialty care, teamwork among frontline clinical teams, and diagnostic error. He formerly served as Vice President for Quality Improvement and Patient Safety and Director of the Center for Patient Safety at Dana-Farber Cancer Institute in Boston. He is the 2012 recipient of the John Eisenberg Award for Patient Safety and Quality from the National Quality Forum and The Joint Commission.

Dr. Weingart earned a bachelor’s degree from Cornell University, a PhD in public policy from Harvard, and an MD from the University of Rochester. He completed a residency and fellowship in internal medicine at Boston’s Beth Israel Deaconess Medical Center. He practices internal medicine at Tufts Medical Center.

Weingart is the former Chair of the National Patient Safety Foundation’s Board of Governors, and recipient of its 2008 Socius Award, honoring work that promotes positive and effective partnering between patients/families and providers in pursuit of improved patient safety. He served on the faculty at Harvard Medical School and Harvard School of Public Health. Dr. Weingart served on the editorial boards of the International Journal for Quality in Health Care and the Joint Commission Journal on Quality and Patient Safety.

Emily Zevon - (Staff Officer)


Event Type :  

Description :   

Achieving Excellence in Sepsis Diagnosis, sponsored by the Gordon and Betty Moore Foundation, will examine the current scientific landscape and research opportunities for improving sepsis diagnosis within the U.S. health care system.

Slides and videos of presentations will be archived on this website after the workshop.

Registration for in Person Attendance :   

If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Anesia Wilks
Contact Email:
Contact Phone:  (202) 334-2166

Supporting File(s)
Is it a Closed Session Event?

Publication(s) resulting from the event:




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