Katherine Lewis is Division Leader in Application, Simulation, and Quality Program at Lawrence Livermore National Laboratory (LLNL). In this role, she leads about 160 computer scientists primarily to support the Weapons and Complex Integration Directorate. Additionally, she leads a LLNL project to investigate artificial intelligence and machine learning techniques for solutions in physics simulations. A large part of this project relates to integrating physics knowledge into models and understanding uncertainties in model predictions. Her expertise is in the area of physics simulations with a focus on setup/workflows, involvement of the user community, and machine learning. She began her career at LLNL in June of 1998 in the field of massively parallel mesh generation. Ms. Lewis received her BS in mathematics, with a minor in computer science, from the University of San Francisco.
Paul Mort is a Professor in the Department of Materials Engineering Center for Particulate Products and Processes at Purdue University. Dr. Mort recently joined the Materials Engineering faculty in support of Purdue’s Center for Particulate Products and Processes (CP3). He is globally recognized as an expert in particulate processing and powder technology. He has a demonstrated history of product innovation and driving process efficiency in the consumer goods industry, including 24 years with Procter & Gamble specializing in granular detergents. Dr. Mort is an editor for the journal Powder Technology and consultant with the International Fine Particle Research Institute (IFPRI), working to develop a pipeline of perspective articles for the journal. He is active in linking particle technology with adjacent technical communities, including pharmaceutical processing and process control. Dr. Mort received his PhD from Rutgers University.
Todd Przybycien is a Professor in the Howard P. Isermann Department of Chemical and Biological Engineering at Rensselaer Polytechnic Institute. He works on industrial downstream bioprocessing and on drug delivery and medical device development. Those activities are linked via fundamental interests in biophysics and in colloid and interface science. His approach is to use spectroscopic, optical, physical, simulation, and informatics tools to connect microscopic, molecular-level behavior to macroscopic, process-level engineering decision variables. His current research topics include downstream processing development of next-generation macromolecular affinity chromatography media based on PEGylated ligands; chromatographic performance as a function of systematic and stochastic uncertainty in mobile phase delivery; continuous precipitation-based processes for protein purification; protein-drug delivery to overcome interfacial denaturation in the delivery of proteins from poly(lactide-co-glycolide) microspheres via protein PEGylation; enhancing spreading, mucolysis, and antimicrobial activity in pulmonary drug delivery with surfactants; and protein adsorption topics impact of micro-scale and nano-scale surface features on protein adsorption behavior. Dr. Przybycien received his PhD in chemical engineering from California Institute of Technology
Kelley Rogers is the Technical Program Manager for the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) at the National Institute of Standards and Technology (NIST) Office of Advanced Manufacturing (OAM). As the Technical Program Manager, Dr. Rogers is responsible for technical quality and coordination with NIIMBL, a NIST-sponsored Manufacturing USA institute whose mission is to accelerate biopharmaceutical manufacturing innovation in the United States. She is currently on detail from NIST’s Material Measurement Laboratory, where she serves as the Technical Program Director for Biosciences and Health. In previous positions, Dr. Rogers worked as a Principal Investigator identifying novel targets for antimicrobial drugs within the pharmaceutical industry. She was a postdoctoral fellow and staff fellow in the National Institute of Digestive, Diabetes, and Kidney Diseases (NIDDK) at the National Institutes of Health. Her research background is in bacterial protein synthesis and gene expression. Dr. Rogers received a PhD in molecular biophysics and biochemistry from Yale University.
Saly Romero-Torres is a Senior Manager of Advanced Data Analytics at Biogen where she leads a team of mathematicians, statisticians, and advanced process control engineers. She has over 15 years of experience in the field of process analytical technologies and advanced manufacturing of biopharmaceuticals with a focus in the use of advanced sensors, advanced process control, data analytics, machine learning and operational excellence tools. Her personal mission is advancing pharmaceutical manufacturing processes to enhance plant operations and, more important, improving patients’ access to critical therapies. Dr. Romero-Torres received her PhD from Purdue University in analytical chemistry and is also an NC State Biomanufacturing Training and Education Center fellow.
Gregory Stephanopoulos (NAE) is the W. H. Dow Professor of Chemical Engineering and Biotechnology in the Department of Chemical Engineering at Massachusetts Institute of Technology (MIT). His laboratory applies metabolic engineering and synthetic biology to understand and synthesize isoprenoids at industrially relevant levels. His group focuses on the upstream pathway, responsible for supplying the building blocks for all isoprenoids, primarily through the microbial 2-methyl-(D)-erythritol-4-phosphate pathway. The work is performed though methods, such as multivariate modular engineering of pathways, to find the optimal expression levels of pathway genes and through the use of novel arrangements of co-cultured organisms. Those strategies, among others, have enabled his laboratory to create platforms for high-level production of isoprenoids. His group also focuses on production of individual isoprenoids, with a large focus on heterologous production of the anticancer drug Taxol (Paclitaxel). They have successfully produced gram-scale titers of the first cyclized precursor and have performed enzymatic studies to reveal previously unknown bottlenecks and methods by which these bottlenecks may be alleviated. Dr. Stephanopoulos has co-authored or edited five books, more than 360 papers, and 50 patents. He is presently the editor-in-chief of Metabolic Engineering and Current Opinion in Biotechnology and serves on the editorial boards of seven scientific journals and the advisory boards of five chemical engineering departments. For his research and educational contributions, Dr. Stephanopoulos has been recognized with numerous awards. In 2003, he was inducted into the National Academy of Engineering (NAE). Dr. Stephanopoulos received his PhD in chemical engineering from the University of Minnesota.
Seongkyu Yoon is Professor in the Francis College of Engineering at the University of Massachusetts (UMass), Lowell. Currently Dr. Yoon is working as a co-director of Massachusetts Biomanufacturing Center, is the UMass site director of the National Science Foundation Industry–University Cooperative Research Centers Program Research Center and the Advanced Mammalian Biomanufacturing Innovation Center, and the UMass technical lead for ManufacturingUSA in Biomanufacturing. His research interests include process system engineering, systems biotechnology, bioprocess innovation, regulatory sciences, and biomanufacturing innovation. He is leading a systems biology research group while conducting research in systems biotechnology, life science informatics, and regulatory sciences with goals to develop an innovative biomanufacturing platform of protein-cell-gene biotherapeutics. Dr. Yoon received his PhD in chemical engineering from McMaster University, Canada, and his MBA from Babson College.