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Project Information

Project Information


Design and Evaluation of Safer Chemical Substitutions – A Framework to Inform Government and Industry Decisions


Project Scope:

 

An ad hoc committee shall develop and demonstrate a decision framework for evaluating potentially safer substitute chemicals as determined by human health and ecological risks. The committee shall identify the scientific information and tools required by regulatory agencies and industry to improve and increase consideration of potential health and environmental impacts early in the chemical design process.  The decision framework shall be capable of integrating multiple and diverse data streams to support early consideration of potential health and environmental impacts as a part of fit-for-purpose decision making.

 


The framework shall discuss how risk (hazard and potential for human expo
sure and toxicity) and environmental impact (ecological risks) can be characterized for chemical substitutions within the context of the full range of benefits and shortcomings of substitutes, and how tradeoffs between these risks and factors such as product functionality, product efficacy, process safety and resource use can be quantified.

 


In its report, the committee shall describe the framework and provide at least two examples that demonstrate how the framework can be applied by different users in contrasting decision contexts with diverse priorities.   These examples shall include demonstration of how high throughput and high content data streams could inform assessment of potentially safer substitutes early in the chemical development process.

Status: Current

PIN: DELS-BCST-13-02

Project Duration (months): 14 month(s)

RSO: Shelton-Davenport, Marilee

Topic(s):

Biology and Life Sciences
Environment and Environmental Studies
Math, Chemistry, and Physics


Committee Membership

Committee Post Date: 10/17/2013

Dr. David C. Dorman - (Chair)
North Carolina State University

David C. Dorman, DVM, Ph.D., is a professor of toxicology in the Department of Molecular Biosciences of North Carolina State University. The primary objective of his research is to provide a refined understanding of chemically induced neurotoxicity in laboratory animals that will lead to improved assessment of potential neurotoxicity in humans. Dr. Dorman's research interests include neurotoxicology, nasal toxicology, pharmacokinetics, and cognition and olfactory in military working dogs. He served as a member of the National Research Council Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents, as member and chair of two Committees on Emergency and Continuous Exposure Guidance Levels for Selected Submarine Contaminants and the Committee to evaluate Potential Health Risks from Recurrent Lead Exposure to DOD Firing Range Personnel, and as a member of the Committee to Review EPA’s Draft IRIS Assessment of Formaldehyde. He received his DVM from Colorado State University. He completed a combined Ph.D. and residency program in toxicology at the University of Illinois at Urbana-Champaign and is a diplomate of the American Board of Veterinary Toxicology and the American Board of Toxicology.
Dr. Peter Beak
University of Illinois at Urbana-Champaign

Dr. Beak has made fundamental contributions to organic chemistry that have provided unifying concepts and opened new areas of investigation. His work has clarified the effect of molecular environment on structure-stability relationships, provided new reactions that are widely used for chemical synthesis, and identified novel reactive intermediates. His current research involves the determination of reaction trajectories in atom-transfer reactions and investigations of asymmetric reactions. He has held editorships, lectureships, and leadership positions in professional organizations. He has received a number of awards, lectured around the world, and served as research advisor for more than 100 graduate and postdoctoral students who are making significant independent contributions to their fields. Dr. Beak is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. Dr. Beak received his B.A. from Harvard University in 1957 and his Ph.D. from Iowa State University in 1961 and then joined the faculty at Illinois. Professor Beak's research interests are in synthetic, structural, and mechanistic organic chemistry, new reaction processes, synthetic methodology, and reactive intermediates.
Dr. Eric J. Beckman
University of Pittsburgh

Dr. Eric Beckman is the George M. Bevier Professor of Engineering at the University of Pittsburgh Department of Chemical and Petroleum Engineering. He is also a co-director of the Mascaro Sustainability Initiative, a center of engineering that focuses on the design of sustainable communities.
The two main research areas for Dr. Beckman are the use of carbon dioxide as either a solvent or raw material and polymer chemistry and processing. Recent work has focused on emulsion and dispersion polymerization on CO2, copolymerization of CO2 and cyclic ethers to form polycarbonates, generation of hydrogen peroxide in CO2 and the extraction of heavy metals using CO2 technology among other related studies. Dr. Beckman received his B.S. in Chemical Engineering from the Massachusetts Institute of Technology in 1980. After a period of employment with both Monsanto Plastics and Resins and the Union Carbide Corporation, Dr. Beckman went on to earn a Ph.D. in Polymer Chemistry and processing from the University of Massachusetts in 1988. As a postdoctoral student, Dr. Beckman held a research appointment at Battelle’s Pacific Northwest Laboratory.

Dr. Jerome J. Cura
The Science Collaborative

Jerome J. Cura. Ph.D., is an Ecological Risk Assessor and Senior Scientist for Woods Hole Group, Inc. in Falmouth, Massachusetts. He is an adjunct professor at Cape Cod Community College where he teaches Fundamentals of Oceanography. He is an expert in the area of ecological risk analysis. He has conducted ecological risk analyses in various freshwater systems, in marine and estuarine habitats, and in terrestrial environments. He has developed guidance for conducting risk assessments at dredging sites for the United States Army Corps of Engineers and he chaired the International Navigation Association’s (PIANC) workgroup that developed international guidance. Dr. Cura’s experience includes conducting assessments at CERCLA and RCRA sites (industrial and government facilities), providing technical advice on the design and execution of human health and ecological risk assessments, and providing expert testimony for law firms. Industry and Government organizations frequently invite him to lead or participate in environmental conferences or symposia. Dr. Cura is a member of the Science Collaborative, a network of senior level environmental scientists. He was a founding partner of Cura Environmental and Menzie-Cura & Associates, Inc. Dr. Cura has published over 30 peer-reviewed book chapters, technical papers, journal articles, and conference proceedings in the areas of risk assessment, environmental decision making, marine ecology, and dredged material disposal evaluation methods. He is a frequent contributor to Scientific Symposia. Dr. Cura received his B.A. in Biology from the College of the Holy Cross in 1971, M.S. in Biology from Northeastern University in 1974 and Ph.D. in Biological Oceanography from the University of Maine in 1981.
Dr. Anne Fairbrother
Exponent, Inc.

Anne Fairbrother, Ph.D., has more than 30 years of experience in ecotoxicology, wildlife toxicology, contaminated site assessment, and regulatory science. She has conducted small and large-area (>100 sq. mile) risk assessments at contaminated sites in tropical, desert, and mountain ecosystems, determining risk thresholds for plants and wildlife. She provided consultation on future development of mine pit lakes, assessed the risk to livestock from use of wastewater on irrigated pasture during mine closure operations, and conducted several assessments of risk to terrestrial and aquatic organisms from mercury. She also assessed risks to wildlife at sites contaminated with organic chemicals, including DDT, PCBs, dioxins, and petroleum hydrocarbons in Delaware, Texas, Oregon, Washington, and California. Dr. Fairbrother has supported industry groups and government agencies in compiling and reviewing literature and industry reports in support of U.S., Canadian, and European regulatory processes for pesticide and chemical risk management. She has testified in front of boards of review and science advisory boards, and prepared expert testimony on environmental risks of pollutants for legal cases within the U.S. Dr. Fairbrother has published more than 90 peer-reviewed articles and book chapters that reflect her expertise in wildlife toxicology, immunotoxicology, endocrine-disrupting chemicals, and ecological risk assessment. She serves on numerous scientific boards, expert panels, and editorial boards in support of scientific and regulatory issues. A veterinarian and certified wildlife biologist, Dr. Fairbrother served as President of the Society of Environmental Toxicology and Chemistry, American Association of Wildlife Veterinarians, and Wildlife Disease Association (WDA). She is the recipient of the WDA Distinguished Service Award (2002), and a gold medal for Commendable Service from EPA. Dr. Fairbrother holds an adjunct professorship at Oregon State University, Department of Environmental, and Molecular Toxicology.
Dr. Nigel Greene
Pfizer Inc.

Nigel Greene, Ph.D., is an Associate Research Fellow with Pfizer Global Research Company specializing in compound safety prediction. His specific duties include establishing and managing a group of Ph.D. level scientists using computational modeling and analysis to help predict the safety profile of early discovery programs and aid in chemical series and compound selection prior to first in vivo studies using chemical properties and in vitro assay profiles. Dr. Greene’s other activities include the mining of internal and public databases of gene expression data to explore biological mechanisms of toxicity and aid in the development of new in vitro assays for safety profiling by conducting in vitro experiments to try to confirm the computational hypotheses derived from these transcriptional databases. Dr. Nigel Greene holds a Ph.D. in Organometallic Chemistry; his thesis entitled “Organophosphorus Transition Metal Chemistry” was received from the University of Leeds (1994) and a B.S. in Chemistry and Computational Science from the University of Leeds (1991).
Dr. Carol J. Henry
The George Washington University

Carol J. Henry, PhD, is a Professorial Lecturer at the George Washington University School of Public Health and Health Services, Department of Environmental and Occupational Health and an advisor and consultant to public and private organizations, focusing on issues in toxicology, public and environmental health, risk assessment and risk management, research management strategies, and green chemistry and engineering technology and sustainable practices. She was previously Vice President of Industry Performance Programs at the American Chemistry Council; Director of the Health and Environmental Sciences Department of the American Petroleum Institute; Associate Deputy Assistant Secretary for Science and Risk Policy at the U.S. Department of Energy; and Director of the Office of Environmental Health Hazard Assessment (OEHHA) at the California Environmental Protection Agency. She is a diplomat of the American Board of Toxicology, certified in general toxicology. She was chair of the Federal Advisory Committee for the National Children’s Study from 2010-2012. She is a member of the Joint Committee on the ANSI NSF Green Chemistry Institute Greener Chemical Products and Processes Standard Initiative, the Environmental Health Perspectives Editorial Board, and the National Research Council’s Board on Chemical Sciences and Technology. She is an elected Councilor for the American Chemical Society (ACS) and serves on the ACS Committee for Environmental Improvement. Dr. Henry received her undergraduate degree in chemistry from the University of Minnesota and doctorate in microbiology from the University of Pittsburgh.
Ms. Helen Holder
Hewlett-Packard Company

Helen Holder, M.S., is a Master Engineer at Hewlett-Packard, where she leads the Global Environmental Materials (GEM) team. In her current role, she evaluates and qualifies materials for use in HP products, including plastics and additives, solders, fluxes, printed circuit board surface finishes, and other electronic materials. In this role, she has introduced environmental and human health criteria into technical specifications to complement traditional performance, cost, safety, and reliability requirements in materials selection. Ms. Holder started her career at HP in 1993, and has worked in a variety of manufacturing, materials, and procurement roles within the company. She received her Bachelor of Science from the Massachusetts Institute of Technology and her Master’s degree from the University of California at Berkeley, where she was an HP Resident Fellow.
Dr. James E. Hutchison
University of Oregon

James E. (Jim) Hutchison, Ph.D., joined the faculty at the University of Oregon (UO) in the fall of 1994. He now holds the Lokey-Harrington Chair in Chemistry. His research interests are in green chemistry, materials chemistry, and nanoscience. He led the development of the UO's nation-leading curriculum in "green" (environmentally benign) organic chemistry, launched the university’s pioneering center in greener nanoscience and is a member of the Governing Board of the ACS Green Chemistry Institute. He is a member of the leadership team for the Oregon Nanoscience and Microtechnologies Institute (ONAMI) and founded, and now directs, the ONAMI’s Safer Nanomaterials and Nanomanufacturing Initiative (SNNI). He is the author of more than 100 refereed publications, three book chapters and a textbook ("Green Organic Chemistry: Strategies, Tools, and Laboratory Experiments"). Dr. Hutchison received a B.S. from the University of Oregon in 1986, a Ph.D. in Organic Chemistry from Stanford University in 1991 and completed postdoctoral studies at the University of North Carolina at Chapel Hill from 1992-1994.
Mr. Gregory M. Paoli
Risk Sciences International

Greg Paoli, M.A.Sc., serves as Principal Risk Scientist and Chief Operating Officer at Risk Sciences International, a consulting firm specializing in risk assessment, management and communication in the field of public health, safety and risk-based decision-support. Mr. Paoli has experience in diverse risk domains including toxicological, microbiological, and nutritional hazards, air and water quality, adaptation to climate change, safety of engineering devices, as well as emergency planning and response for natural and man-made disasters. He specializes in risk assessment methods, the development of risk-based decision-support tools and comparative risk assessment. Mr. Paoli has served on a number of expert committees devoted to the risk sciences. He was a member of the National Research Council's Committee on Improving Risk Analysis Approaches Used by the USEPA, that issued the 2009 report, Science and Decisions: Advancing Risk Assessment. He serves on an NRC Standing Committee on the use of public health data at the U.S. Food Safety and Inspection Service, and has served on several expert committees convened by the World Health Organization. He serves on the Standards Council of Canada Technical Committee on Risk Management and served on advisory committees of the National Roundtable on the Environment and the Economy. Mr. Paoli completed a term as Councilor of the Society for Risk Analysis (SRA) and is a member of the Editorial Board of Risk Analysis. Recently, Mr. Paoli was awarded the Sigma Xi - SRA Distinguished Lecturer Award. Greg holds a B.A.Sc. in Electrical and Computer Engineering and a M.A.Sc. in Systems Design Engineering from the University of Waterloo.
Dr. Julia B. Quint
California Department of Public Health [Retired]

Julia Quint, Ph.D., is retired from the California Department of Public Health (CDPH), where she was Research Scientist and Chief of the Hazard Evaluation System and Information Service (HESIS), an occupational health program. She has a Ph.D. in Biochemistry from the University of Southern California. Throughout her career as a public health scientist, Julia has initiated, developed, and contributed to projects, programs, and policies that are focused on protecting workers, communities, and the environment from toxic chemicals, and on promoting the development and use of safer alternatives to toxic chemicals. She has served on a number of scientific advisory committees, including committees of the National Academy of Sciences (NAS) on tetrachloroethylene, health impact assessment, and review of the Department of Labor’s Site Exposure Matrix Database, the Cal/OSHA Health Expert Advisory Committee, and the Cal/EPA’s Green Ribbon Science Panel. She currently serves on the Scientific Guidance Panel of the California Biomonitoring Program, the CDC/NIOSH World Trade Center Scientific and Technical Advisory Committee, the UCSF Program on Reproductive Health and the Environment’s From Advancing Science to Ensuring Protection Advisory Group, the National Healthy Nail Salon Alliance Research Advisory Committee, and the CDPH Environmental Health Tracking Advisory Group. Dr. Quint has authored many peer-reviewed scientific articles and reports, and is the recipient of several awards for her work in public health.
Dr. Ivan Rusyn
The University of North Carolina at Chapel Hill

Ivan Rusyn, M.D., Ph.D., is Professor in the Department of Environmental Sciences and
Engineering in the Gillings School of Public Health at the University of North Carolina at Chapel Hill. He directs the Laboratory of Environmental Genomics and the Carolina Center for Computational Toxicology. He also is a member of the Lineberger Comprehensive Cancer Center, Center for Environmental Health and Susceptibility, Bowles Center for Alcohol Studies, and the Carolina Center for Genome Sciences. Dr. Rusyn served on several working groups convened by the National Research Council and the WHO/IARC. Dr. Rusyn's laboratory has an active research portfolio funded by the National Institutes of Health and the U.S. EPA with a focus on the mechanisms of action of environmental toxicants and the genetic determinants of the susceptibility to toxicant-induced injury. The Rusyn laboratory applies molecular, biochemical, genetic and genomic approaches to understanding the mechanisms of environmental agent-related disease. His studies on health effects of environmental agents resulted in more than 135 peer-reviewed publications. Dr. Rusyn received his M.D. (with honors) from Ukrainian State Medical University in Kiev and his Ph.D. in Toxicology from the University of North Carolina at Chapel Hill. He also trained at the University of Dusseldorf in Germany and at the Massachusetts Institute of Technology.

Dr. Kathleen A. Shelton
DuPont Haskell Global Centers for Health and Environmental

Dr. Kathleen Shelton, Ph.D., is Director of DuPont Haskell Global Centers for Health and Environmental Sciences. She is the director of Technology for DuPont’s Crop Protection business. Dr. Shelton is responsible for the leadership of the business’ discovery and development efforts, globally, and for assuring that the business has a full and valuable pipeline of new products. In June 2013, she was selected by the Health and Environmental Sciences Institute (HESI) Board of Directors as a member of the Emerging Issues Committee. Dr. Shelton is also Director of Central Research and Development, Enabling Technologies, and is responsible for leading the organizations that provide analytical, computational, and pilot scale services across DuPont. Dr. Shelton has worked at DuPont in various capacities since 1993. Recently, she was detailed to Geneva, Switzerland, where she led European advocacy efforts related to REACH (registration, evaluation, authorization and restriction of chemical substances) implementation and chemicals management, including participation in the Product Stewardship Programme Council of the European Chemical Industry Association (CEFIC) and the Strategic Approach to International Chemicals Management (SAICM, part of the United Nations Environmental Programs). Dr. Shelton has a B.S. in Biology from the University of Notre Dame, and a Ph.D. in Microbiology and Immunology from Hahnemann University (now part of Drexel University).
Dr. Joel A. Tickner
University of Massachusetts

Dr. Joel A. Tickner, Sc.D., is an associate professor in the Department of Community Health and Sustainability of the University of Massachusetts Lowell. He is interested in the development of innovative scientific methods and policies to implement a precautionary and preventive approach to decision-making under uncertainty while advancing assessment and adoption of safer substitutes to chemicals and products of concern. His teaching and research interests include regulatory science and policy, risk assessment, pollution prevention, cleaner production, and environmental health. Dr. Tickner has served on several advisory boards and as an expert reviewer, most recently for the California Green Chemistry Initiative, the US Environmental Protection Agency National Pollution Prevention and Toxics Advisory Committee, and the First National Precautionary Principle Conference Advisory Committee. He is the recipient of several honors and awards, including the University of Massachusetts President’s Award for Public Service, the National Pollution Prevention Roundtable Champion Award, and the North American Hazardous Waste Managers Policy Leader Award. Dr. Tickner earned an ScD in cleaner production and pollution prevention from the University of Massachusetts Lowell.
Dr. Adelina Voutchkova
The George Washington University

Dr. Adelina Voutchkova is an Assistant Professor of Chemistry in the Department of Chemistry at George Washington University. Dr. Voutchkova has substantial experience in the areas of molecular design, toxicology and green chemistry. Her work aims at developing rational guidelines for the design of industrial chemicals that are acutely and chronically safe to a variety of aquatic families of species, including fish, crustaceans and algae. Specific projects include the development of product design guidelines for chronic mammalian toxicity and the utilization of spectroscopic data to inform safer molecular design, with specific interests in minimizing skin sensitization from personal care products. Dr. Voutchkova earned her B.A. from Middlebury College and Ph.D. from Yale University in 2008.
Mr. Martin H. Wolf
Seventh Generation, Inc.

Martin Wolf is Director, Product Sustainability & Authenticity for Seventh Generation Inc. In this capacity, Mr. Wolf is responsible for assuring the sustainable design of products at Seventh Generation Inc., a manufacturer and distributor of ecological household and personal care products. He has over 40 years of experience in industrial and environmental chemistry, initially examining environmental fate and metabolism studies for agricultural chemicals and later studying the occurrence of hazardous chemicals in the environment, conducting life cycle studies of industrial processes, and designing more sustainable household cleaning products. In addition to his work for Seventh Generation, he serves as Chair of the Sustainability Committee, and has served as the Chair of the Strategic Advisory Committee (2009-2011), as Vice Chair of the Sustainability Committee (2010-2012), and as Vice Chair of the Asthma Task Group, of the American Cleaning Institute (formerly the Soap & Detergent Association). Mr. Wolf received a 2010 EPA Environmental Merit Award for his work. He holds a master's degree in Chemistry from Yeshiva University and a bachelor’s in Chemistry from Worcester Polytechnic Institute.

Committee Membership Roster Comments

Note (10/17/2013): There has been a change in committee membership with the appointment of Martin H. Wolf.

Events



Location:

12:30pm - 2:00pm EDT
Online Webinar
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Ivory Clarke
Contact Email:  iclarke@nas.edu
Contact Phone:  202-334-1942

Agenda
To join the Webinar you must register at the link below. You will use the same link to join the webinar on October 24, 2014, beginning at 12:30 PM EDT.

https://nasevents.webex.com/nasevents/onstage/g.php?t=a&d=662936691


Description:
Concerns about the health and environmental impacts associated with some chemical products and processes have motivated a growing number of national, state, and local governments, manufacturers, and retailers to develop assessments and approaches for finding safer chemical substitutes. These existing assessment frameworks reflect a range of different priorities, whether the focus is on protecting workers, the environment, the end users of products, or other interests. The National Research Council report A Framework to Guide Selection of Chemical Alternatives builds on those frameworks to develop a more universally-applicable decision framework for evaluating potentially safer chemical alternatives.

This webinar will feature a presentation from Dr. David Dorman of North Carolina State University, the Chair of the report’s authoring committee, followed by a Q&A session with Dr. Dorman and other committee members.

Below is a link to the complete report:
http://www.nap.edu/catalog.php?record_id=18872
Is it a Closed Session Event?
No



Location:

Keck Center
500 5th St NW, Washington, DC 20001
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Ivory Clarke
Contact Email:  iclarke@nas.edu
Contact Phone:  202-334-1942

Agenda
This meeting is closed in its entirety.
Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

David Dorman
Peter Beak
Eric Beckman
Jerome Cura
Anne Fairbrother (via teleconference)
Nigel Greene
Helen Holder
James Hutchison
Gregory Paoli
Ivan Rusyn
Joel Tickner
Adelina Voutchkova
Martin Wolf


The following topics were discussed in the closed sessions:

1) The draft report and report organization
2) Committee conclusions and recommendations
3) Committee assignments and report review schedule


The following materials (written documents) were made available to the committee in the closed sessions:

None

Date of posting of Closed Session Summary:
May 12, 2014


Location:

National Academy of Sciences Building
2101 Constitution Ave NW, Washington, DC 20418
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Ivory Clarke
Contact Email:  iclarke@nas.edu
Contact Phone:  (202) 334-1942

Agenda
Agenda Subject to Change.

Please let us know you are coming by sending a registrant e-mail to Ivory Clarke (iclarke@nas.edu)
The e-mail should include: First and Last Name, Job Title and Institution.

To LISTEN ONLY via WebEx please use the following links:

Thursday, February 6, 2014 (3:00 pm - 5:30 pm EST)
Go to https://nationalacademies.webex.com/nationalacademies/j.php?ED=235999817&UID=1615911817&RT=MiMxMQ%3D%3D

Friday, February 7, 2014 (10:00 am - 12:00 pm EST)
https://nationalacademies.webex.com/nationalacademies/j.php?ED=235999702&UID=1615912837&RT=MiMxMQ%3D%3D

Open Session AGENDA
Thursday, February 6

OPEN SESSION

3:00 Discussion of Life Cycle Analysis and Thinking
Thomas McKone, University of California, Berkeley
By Phone or Web Conference

4:00 Discussion of New Data Streams and Their Use
Russell Thomas, EPA
By Phone or Web conference

5:30 Adjourn


Friday, February 7

10:00 Discussion of New Data Streams and Their Use
Kristina Thayer, NIEHS/NTP, By Phone or Web Conference

11:00 Caroline Baier-Anderson, EPA

12:00PM END OF OPEN SESSION
Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

David Dorman (Chair)
Peter Beak
Eric Beckman
Jerome Cura
Anne Fairbrother
Nigel Greene
Carol Henry
Helen Holder
James Hutchison
Gregory Paoli
Julia Quint
Ivan Rusyn
Kathleen Shelton
Joel Tickner
Adelina Voutchkova
MArtin Wolf

The following topics were discussed in the closed sessions:

Discussion of framework.
Discussion of draft and next steps
Discussion of case studies
Planning next steps and schedule

The following materials (written documents) were made available to the committee in the closed sessions:

28. McKone, Thomas.
2/6/2014.
Email to Program Assistant with PowerPoint presentation for Meeting 3 attached.
“Comparative risk, alternatives, & life-cycle-impact assessments: Tools for addressing safer chemicals?”
29. Thomas, Russell.
2/5/2014.
Email to Program Assistant with PowerPoint presentation for Meeting 3 attached.
“EPA Follow-Up Briefing to Chemical Substitutions Committee.”
30. Thayer, Kristina.
2/6/2014.
Email to Program Assistant with PowerPoint presentation for Meeting 3 attached.
“NTP Activities on BPA Analogues .”


Date of posting of Closed Session Summary:
February 19, 2014


Location:

teleconference
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Kathryn Hughes
Contact Email:  khughes@nas.edu
Contact Phone:  202-334-2156

Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

Peter Beak
Eric Beckman
Carol Henry
Helen Holder
Greg Paoli
Joel Tickner
Martin Wolf

The following topics were discussed in the closed sessions:

Drafting of the report.

The following materials (written documents) were made available to the committee in the closed sessions:

None

Date of posting of Closed Session Summary:
January 09, 2014


Location:

Arnold and Mabel Beckman Center
100 Academy Way, Irvine, CA 92617
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Ivory Clarke
Contact Email:  iclarke@nas.edu
Contact Phone:  -

Agenda
This meeting is closed in its entirety.
Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

All members present.

The following topics were discussed in the closed sessions:

Proposed Framework
Draft Text
Frameworks and Approaches Already in Existence


The following materials (written documents) were made available to the committee in the closed sessions:

Email from EPA, dated 12/16/13.

Date of posting of Closed Session Summary:
December 20, 2013


Location:

National Academy of Sciences Building
2101 Constitution Ave NW, Washington, DC 20418
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Ivory Clarke
Contact Email:  iclarke@nas.edu
Contact Phone:  -

Agenda
Please let us know you are coming by registering at: http://www.surveygizmo.com/s3/1428391/Design-and-Evaluation-of-Safer-Chemical-Substitutions-Open-Session-Registration

WebEx.https://nationalacademies.webex.com/nationalacademies/j.php?ED=226363107&UID=0&RT=MiMxMQ%3D%3D
To save time, you can setup prior to the meeting by clicking this link:
https://nationalacademies.webex.com/nationalacademies/meetingcenter/mcsetup.php


Agenda-Friday, November 15, 2013

OPEN SESSION

Committee’s Charge and Drivers and Context Behind the Study
9:30 Discussion of Charge and Study Drivers (TAB 3)

What are the policy drivers for this study? What is OCSPP currently doing in-house as related to new chemicals and safer substitutions?
-Jim Jones, Assistant Administrator for the Office of Chemical Safety and Pollution Prevention, Environmental Protection Agency (confirmed)

What are the science drivers for this study? What is the current state of ORD science related to this study?
-Robert Kavlock, Deputy Assistant Administrator for Science, Office of Research and Development, Environmental Protection Agency (confirmed)

11:00 State Context: California Safer Consumer Products Regulation (TAB 9.A)
-Gina Solomon, Deputy Secretary for Science and Health, California Environmental Protection Agency (confirmed, remote participation)

11:30 Discussion
• Committee questions for Jones, Kavlock, and Solomon

12:15 Lunch Break

Frameworks in Use or Development
12:45 OECD Analysis of Frameworks (belongs after Whittaker, moved earlier for lunch break)
-Peter Borkey, OECD Environment Directorate, Secretariat of OECD (confirmed, remote)

1:05 Break

1:20 Overview of Tools and Frameworks (TAB 6.A)
-Margaret Whittaker, Managing Director and Chief Toxicologist, ToxServices (confirmed)

2:00 EPA’s Design for the Environment (TAB 8A & 8B)
-Clive Davies, Chief, Design for the Environment Branch, Environmental Protection Agency (confirmed)

2:20 Multi-Criteria Decision Analysis (TAB 8C)
-Timothy Malloy, Sustainable Technology & Policy Program, UCLA School of Law (confirmed)

2:40 Discussion
• Committee questions for Whittaker, Davies, and Malloy

3:00 Break
Perspectives on Framework Design and Application

3:20 Retailer Perspective (TAB 9B)
-Pamela Gaik, Director, Supplier Collaboration, Sam’s Club (Wal-Mart) with Rob Kaplan Director, Product Sustainability at Wal-Mart and Thomas Head, Product Safety & Regulatory Compliance Manager at Wal-Mart (confirmed)

3:40 Chemical Industry Perspective (TAB 7C)
-Michael Walls, American Chemistry Council (confirmed)

4:00 NGO Perspective (TAB 7A)
-Jennifer McPartland, Environmental Defense Fund (confirmed)

4:20 Discussion
• Committee questions for Walls, McPartland, and Gaik

4:50 Public Comments and Questions about Strengths and Limitations of Existing Approaches:
Priority will be given to commenter’s who have requested time to speak by November 12. Speakers will be limited to 3- 5 minutes of comments, depending on how many requests were received. Register at http://www.surveygizmo.com/s3/1428391/Design-and-Evaluation-of-Safer-Chemical-Substitutions-Open-Session-Registration

5:30 Adjourn

Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

David Dorman
Eric Beckman (Day 1 only)
Peter Beak
Jerome Cura
Anne Fairbrother
Nigel Greene
Carol Henry
Helen Holder
James Huchison
Gregory Paoli
Julia Quint
Ivan Rusyn
Kathleen Shelton
Joel Tickner
Adelina Voutchkova (Day 1 only)
Martin Wolf (Day 1 only)

The following topics were discussed in the closed sessions:

Committee's approach to the statement of task
Study timeline
Committee's composition and balance
Draft outline of the report
Writing assignments
Data-gathering needs

The following materials (written documents) were made available to the committee in the closed sessions:

Briefing book containing the agenda, committee information, background reading, and relevant NRC policies
Supplemental folder containing hardcopies of the presentations and speaker biographies

Date of posting of Closed Session Summary:
November 21, 2013


Location:

Keck Center
500 5th St NW, Washington, DC 20001
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Marilee Shelton-Davenport
Contact Email:  mshelton@nas.edu
Contact Phone:  -

Agenda
This meeting is closed in its entirety.
Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

Present for the discussion on September 20 were committee members David Dorman (chair)
Eric Beckman
Jerome Cura
Carol Henry
and Ivan Rusyn.

The following topics were discussed in the closed sessions:

The purpose of the teleconference was to carry out the bias and conflict discussion with the committee members. Committee composition was also discussed.

The following materials (written documents) were made available to the committee in the closed sessions:

Meeting agenda.

Date of posting of Closed Session Summary:
September 26, 2013


Location:

Keck Center
500 5th St NW, Washington, DC 20001
Event Type :  
-

Registration for Online Attendance :   
NA

Registration for in Person Attendance :   
NA


If you would like to attend the sessions of this event that are open to the public or need more information please contact

Contact Name:  Marilee Shelton-Davenport
Contact Email:  mshelton@nas.edu
Contact Phone:  -

Agenda
This meeting is closed in its entirety.
Is it a Closed Session Event?
Yes

Closed Session Summary Posted After the Event

The following committee members were present at the closed sessions of the event:

Present for the discussion on September 17 were committee members David Dorman (chair)
Anne Fairbrother
Nigel Greene
Helen Holder
James
Hutchison
Gregory Paoli
Joel Pickner
Julia Quint
Kathleen Shelton
and Adelina Voutchkova.

The following topics were discussed in the closed sessions:

The purpose of the teleconference was to carry out the bias and conflict discussion with the committee members. Committee composition was also discussed.

The following materials (written documents) were made available to the committee in the closed sessions:

Meeting agenda.

Date of posting of Closed Session Summary:
September 26, 2013

Publications

  • Publications having no URL can be seen at the Public Access Records Office