Date:  May 7, 2014




National Coordination Needed to Help ’Convergent’ Research Achieve Breakthroughs and Solve Problems that Cross Disciplinary Boundaries


WASHINGTON -- Convergent research – which crosses disciplinary boundaries, integrating tools and knowledge from the life sciences, physical sciences, engineering, and other fields -- could spur innovation and help tackle societal challenges, but greater national coordination is needed, says a new report from the National Research Council. Convergent science still faces hurdles and requires a culture shift for research institutions, which have traditionally organized research around separate disciplines.


Convergent science also relies on forming a web of partnerships to support boundary-crossing research and to translate advances into new products. The report identifies steps institutions and the nation can take to support these partnerships.


“Some of our most difficult real-world problems do not respect disciplinary boundaries, and convergent science, which brings together insights and approaches from many fields, can help us find solutions,” said committee chair Joseph DeSimone, Chancellor’s Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill and the William R. Kenan Jr. Distinguished Professor of Chemical Engineering at NC State. “It is time for a systematic effort to highlight the value of convergence as an approach to R&D, and to address lingering challenges to its effective practice.”


The report identifies areas where convergent approaches could accelerate innovation and help meet broad challenges, including creating new fuels and energy storage systems, meeting the world’s need for secure food supplies in a changing climate, and developing new treatments for chronic illnesses.


Convergent research is already contributing to breakthroughs, the report notes. For example, convergence between the engineering and biotechnology worlds is bringing 3-D printing -- which enables custom objects to be built on demand within hours – to medicine, allowing the construction of medical implants customized to individual patients. Researchers are now working to develop 3-D printers that use living cells to construct human tissues and organs for transplants. Doing so will require integrating knowledge from life sciences on how to sustain cells through the printing process, from materials science on scaffolding to support the cells, and from engineering to design and construct the printing devices. Bringing these advances to doctors and patients will require partnerships with industrial, clinical, and regulatory colleagues.


But barriers to convergent science remain, and institutions often have little guidance on how to establish effective programs. The report identifies strategies used by institutions to support convergence efforts, such as creating research institutes or programs around a common theme, problem, or scientific challenge; hiring faculty in transdisciplinary clusters; and embedding support for convergence in the promotion and tenure process. Convergence efforts can also be informed by economic, social, and behavioral science and humanities research on establishing interdisciplinary cultures, supporting team-based science, and revising STEM education and training.


To accelerate convergence, experts, funding agencies, foundations, and other partners should identify key problems whose solution requires convergence approaches, the report recommends. Research institutions, funding agencies, foundations, and other partners should address barriers to convergence as they arise, and they should expand mechanisms for funding convergence efforts. Seed funding to catalyze collaborations should be implemented or expanded. Leaders and practitioners who have fostered a convergence culture in their organizations and laboratories should develop partnerships with other institutions, helping to nurture their convergence efforts.


To most effectively achieve such goals and move beyond the current patchwork of convergence efforts, greater coordination will be needed, the report says.  National coordination on convergence would provide a platform for agencies that support biomedical research, such as the National Institutes of Health, and those that support research in the physical sciences, such as the National Science Foundation and the U.S. Department of Energy, to identify opportunities for collaboration. The power of such cross-agency efforts is illustrated by the success of the Human Genome Project, a collaborative effort of NIH and DOE.


Many stakeholders can be involved in the national coordination needed to advance convergence, the report says. For example, associations and societies can undertake convening efforts to set goals. Foundations could serve catalytic roles for the community. Cross-agency working groups could coordinate policy development. All of these actors can play vision-setting roles in establishing new strategies to facilitate convergence.


The study was sponsored by the Raymond and Beverley Sackler Science Fund of the National Academy of Sciences; the Burroughs Wellcome Fund; Kavli Foundation; Research Corporation for Science Advancement; National Science Foundation, National Institutes of Health; William R. Kenan, Jr. Institute for Engineering, Technology, and Science of North Carolina State University; Frank Hawkins Kenan Institute of Private Enterprise of the University of North Carolina at Chapel Hill; and the Connecticut Institute for Clinical and Translational Science at the University of Connecticut. 


The National Academy of Sciences, National Academy of Engineering, Institute of Medicine, and National Research Council make up the National Academies.  They are private, independent nonprofit institutions that provide science, technology, and health policy advice under a congressional charter granted to NAS in 1863.  The National Research Council is the principal operating arm of the National Academy of Sciences and the National Academy of Engineering.  For more information, visit  A committee roster follows.

Additional Resources:
Report in Brief


Sara Frueh, Media Relations Officer

Office of News and Public Information

202-334-2138; e-mail

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Division on Earth and Life Studies

Board on Life Sciences


Committee on Key Challenge Areas for Convergence and Health

Joseph M. DeSimone1,2 (chair)

William R. Kenan Jr. Distinguished Professor of Chemical Engineering

North Carolina State University; and

Director, Frank Hawkins Kenan Institute of Private Enterprise, and

Chancellor’s Eminent Professor of Chemistry

University of North Carolina

Chapel Hill


Timothy Galitski

Affiliate Professor

Institute for Systems Biology; and

Former Head of Science and Technology

EMD Millipore Corp.



James M. Gentile

Dean for the Natural and Applied Sciences

Hope College

Holland, Mich.


Sharon C. Glotzer

S.W. Churchill Collegiate Professor of Chemical Engineering,

Professor of Materials Science and Engineering, and
Professor of Physics, Applied Physics, and Macromolecular Science and Engineering

University of Michigan

Ann Arbor


Susan M. Hockfield

President Emeritus and Professor of Neuroscience

Massachusetts Institute of Technology



Julie Thompson Klein

Professor of Humanities

English Department, and

Faculty Fellow for Interdisciplinary Development

Wayne State University

Ypsilanti, Mich.


Cato T. Laurencin2,3

Director, Institute for Regenerative Engineering,

Chief Executive Officer, Connecticut Institute for Clinical and Translational Science,

Van Dusen Chair in Academic Medicine, and

Distinguished Professor of Orthopaedic Surgery and Chemical, Materials, and Biomolecular Engineering,

UConn Health Center



Cherry A. Murray1,2


School of Engineering and Applied Sciences

Harvard University

Cambridge, Mass.


Monica Olvera de la Cruz1

Director, Materials Research Center, and

Lawyer Taylor Professor of Materials Science and Engineering, Chemistry, and (by courtesy) Chemical and Biological Engineering

Northwestern University

Evanston, Ill.


Nicholas A. Peppas2,3

Fletcher Stuckey Pratt Chair in Engineering

Department of Biomedical Engineering, and


Departments of Chemical Engineering and Biomedical Engineering and College of Pharmacy

University of Texas



Lynne J. Regan

Professor of Molecular Biophysics and Biochemistry,

Professor of Chemistry, and

Director, Integrated Graduate Program in Physical and Engineering Biology

Yale University

New Haven, Conn.


J. David Roessner

Senior Fellow

Center for Science, Technology, and Economic Development

SRI International

Redwood City, Calif.




Katherine Bowman

Study Director



1 Member, National Academy of Sciences

2 Member, National Academy of Engineering

3 Member, Institute of Medicine