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News from the National Academies
Date: July 1, 2003
Contacts: Christine Stencel, Media Relations Officer
Andrea Durham, Media Relations Assistant
Office of News and Public Information
(202) 334-2138; e-mail <news@nas.edu>

Report Recommends Steps to Reduce Dietary Dioxin Exposure

WASHINGTON -- A federal interagency group should develop and implement an integrated risk-management strategy and action plan to reduce human exposure to dioxins in foods, says a new report from the Institute of Medicine of the National Academies. Government officials should collaborate with the private sector to identify and pursue voluntary interventions to further minimize levels of these toxic compounds in human foods and animal feeds. However, the health risks posed by the levels of dioxins in foods have yet to be ascertained, so the report does not recommend regulatory limits on dioxins or dioxin-like compounds (DLCs) in food or feed.

Since fetuses and infants are especially sensitive to the effects of toxic compounds, one part of the government's action plan should be an effort to reduce girls' and women's exposure to dioxins in foods during the years well before childbearing, so that less of these compounds accumulate in their bodies and are passed on through the placenta and breast milk, the report adds. By promoting compliance with current dietary recommendations to consume less animal fat -- where dioxins primarily collect -- the government could help all Americans reduce their exposure to these compounds.

"Because the risks posed by the amount of dioxins found in foods have yet to be determined, we are recommending simple, prudent steps to further reduce dioxin exposure while data are gathered that will clarify the risks, " said Robert Lawrence, associate dean for professional practice and programs, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, and chair of the committee that wrote the report.

Dioxins and DLCs are long-lasting compounds that accumulate in the body fat of animals and people. Although dioxins are ubiquitous in the environment, the fats in meat, poultry, fatty fish, whole milk, and full-fat dairy products are the principal source of most people's exposure. However, fetal and infant exposure depends on the amount in the mother's body because these compounds can cross the placenta and also collect in the fat in breast milk.

High levels of dioxins have been linked to endocrine-related conditions, developmental problems, and susceptibility to cancer, among other health hazards. However, more research is needed to discern whether small amounts of dioxins are toxic and at what levels they begin to pose risks. Further improvements in analytical tools and methods will enable researchers to better characterize any possible risks associated with low-level exposure. Dioxin levels in the environment have declined dramatically in recent decades -- by as much as 76 percent since the 1970s, according to some measurements. Dioxin levels in foods have decreased greatly as well.

The committee was not asked to offer any judgments about the risks of human exposure through foods, but rather to recommend risk-management options that would further reduce dioxin exposure among the general population and vulnerable groups until the health risks are defined. The report recommended no mandatory limits on dioxins, given the current lack of precise data on both the risks and the current amounts of the compounds in foods and feeds.

Minimizing girls' and young women's intake of dioxins during the years before pregnancy is the only practical way to reduce dioxin exposure in fetuses and breast-feeding infants, the report says. Given the health and social benefits of breast-feeding, the committee recommended strategies to reduce accumulated body levels of dioxin, rather than to discourage breast-feeding.
To reduce dioxin exposures in all children -- especially girls -- government-sponsored food programs, such as the National School Lunch Program, should increase the availability of foods low in animal fat. For example, low-fat milk should be made more widely available in the school lunch program. Also, the U.S. Department of Agriculture should analyze the impact of setting limits on the amount of saturated fat that can be present in meals served in the school breakfast and lunch programs. Except for children under age 2, participants in the Special Supplemental Food Program for Women, Infants, and Children should be encouraged to choose low-fat milk and foods.

Promoting compliance with the Dietary Guidelines for Americans on consumption of saturated fats and fats in general would minimize people's dioxin exposure without compromising their intake of nutrients. Because of the health benefits associated with omega-3 fatty acids in fish and the difficulty of trimming fat from fish, the committee did not recommend that people reduce their consumption of fatty fish below the currently recommended two servings per week.

The committee also urged the government to give priority to reducing dioxin contamination of animal feed, and to curtailing the recycling of dioxins that occurs when contaminated grass forage and animal fat are included as ingredients in feed. Federal agencies should work with food producers to develop voluntary guidelines for animal feeding and food-production practices that would minimize animals' exposure to dioxins.

The report was sponsored by the U. S. Department of Health and Human Services, Food and Drug Administration, and agencies within the U. S. Department of Agriculture. The Institute of Medicine is a private, nonprofit institution that provides health policy advice under a congressional charter granted to the National Academy of Sciences. A committee roster follows.
Copies of Dioxins and Dioxin-like Compounds in the Food Supply: Strategies to Decrease Exposure will be available later this year from the National Academies Press; tel. (202) 334-3313 or 1-800-624-6242 or on the Internet at http://www.nap.edu. Reporters may obtain a pre-publication copy from the Office of News and Public Information (contacts listed above).


Institute of Medicine
Food and Nutrition Board

Committee on the Implications of Dioxins in the Food Supply

Robert S. Lawrence, M.D. (chair)
Associate Dean
Professional Education Programs;
Edyth Schoenrich Professor of Preventive Medicine; and
Professor of Health Policy
Bloomberg School of Public Health
Johns Hopkins University
Baltimore

Dennis M. Bier, M.D.
Professor of Pediatrics;
Director, USDA Children's Nutrition Research Center; and
Program Director, NIH General Clinical Research Center
Baylor College of Medicine
Houston

Robert E. Broyles
Consultant
Purina Mills Inc. (retired)
Chesterfield, Mo.

Dorothy R. Caldwell, M.S., R.D., L.D.N.
Coordinator
Initiative for Healthy Weight in Children and Youth
North Carolina Division of Public Health, and Adjunct Assistant Professor
School of Public Health
University of North Carolina
Raleigh

David O. Carpenter, M.D.
Professor of Environmental Health and Toxicology, and
Director
Institute for Health and the Environment
School of Public Health
University at Albany
State University of New York
Rensselaer

Julie A. Caswell, Ph.D.
Professor
Department of Resource Economics
University of Massachusetts
Amherst

Keith R. Cooper, Ph.D.
Professor and Associate Dean of Research
New Jersey Agricultural Experiment Station
Cook College
Rutgers University, and
Associate Director
Joint Graduate Program in Toxicology
National Institute of Environmental Health Sciences Training Grant
New Brunswick

James K. Hammitt, Ph.D.
Professor of Economics and Decision Sciences
Department of Health Policy and Management, and
Center for Risk Analysis, and
Director of Environmental Science and Risk Management
School of Public Health
Harvard University
Boston

Gail G. Harrison, Ph.D.
Professor and Chair
Department of Community Health Services
School of Public Health;
Associate Director for Public Health Programs
Center for Human Nutrition; and
Assistant Director
Program for Healthy and At-Risk Populations
Division of Cancer Prevention and Control
Jonsson Comprehensive Cancer Center
University of California
Los Angeles

James T. Heimbach, Ph.D.
Principal
ENVIRON International Corp.
Arlington, Va.

Barbara A. Knuth, Ph.D.
Professor of Natural Resource Policy and Management
Department of Natural Resources
Cornell University
Ithaca, N.Y.

James D. McKean, D.V.M., M.S., J.D.
Extension Veterinarian and Professor
Department of Veterinary Diagnostic and Production Animal Medicine
College of Veterinary Medicine
Iowa State University
Ames

Pieter J.J. Sauer, M.D., Ph.D.
Professor and Chair
Department of Pediatrics
University Hospital
University of Groningen
Groningen
Netherlands

Robert E. Smith, Ph.D.
President
R.E. Smith Consulting Inc.
Newport, Vt.

Michael R. Taylor, J.D.
Senior Fellow and Director
Risk Resource and Environmental Management Division
Resources for the Future
Washington, D.C.

Katherine L. Tucker, Ph.D.
Director
Dietary Assessment Research Program,;
Scientist
National Epidemiology Program
Jean Mayer USDA Human Nutrition Research Center on Aging; and
Associate Professor
School of Nutrition Science and Policy
Tufts University
Boston

INSTITUTE STAFF

Ann Yaktine, Ph.D.
Study Director