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Project Title:

Prophylactic Use of Antiviral Medications during an Influenza Pandemic
PIN: PHPH-H-07-15-A        

Major Unit:

Institute of Medicine

Sub Unit: Board on Population Health and Public Health Practice

RSO: Baciu, Alina

Subject/Focus Area: Health and Medicine


Project Scope
An IOM committee will plan and convene a workshop of State and local pandemic influenza planners, as well as national and relevant international influenza experts, to consider best practices and policies for implementing a pandemic influenza antiviral drug program. Components of the program to be addressed include treatment of cases, post-exposure prophylaxis for their household contacts, and prophylaxis of "front-line" healthcare workers and emergency service personnel. With respect to treatment of cases and post-exposure of their household contacts, key planning issues include but are not limited to determining where drugs dispensed; allocation and distribution of drugs to those sites; diagnostic approach for cases; strategy to enumerate household contacts and assess appropriateness of dispensing drugs for them; potential regulatory barriers to dispensing; and monitoring antiviral drug use and safety. With respect to prophylaxis for targeted healthcare and emergency services personnel, key issues include but are not limited to determining where drugs are dispensed; potential regulatory barriers to dispensing; labor issues that may arise from targeting some workers but not others; and monitoring antiviral drug use and safety. The committee will review current State plans, lessons learned from drills and exercises, and will explore the challenges and barriers to rapid and efficient distribution of the drugs for treatment and prophylaxis in the general population and in targeted occupationally defined groups. The committee will issue a brief report with conclusions and recommendations regarding components of an effective antiviral program for patients and their household contacts and for prophylaxis of healthcare and emergency service personnel.

The project is sponsored by the U.S. Department of Health and Human Services.

The approximate start date for the project was October 2007.


 
Project Duration: 9 months    

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Committee Membership
Committee Membership

Meetings
 Meeting 1 - 12/03/2007
 Meeting 2 - 01/07/2008

Reports

Reports having no URL can be seen
at the Public Access Records Office
Antivirals for Pandemic Influenza: Guidance on Developing a Distribution and Dispensing Program


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