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Project Title:

Industrialization of Biology: A Roadmap to Accelerate Advanced Manufacturing of Chemicals
PIN: DELS-BCST-13-01        

Major Unit:

Division on Earth and Life Studies

Sub Unit: Board on Chemical Sciences and Technology
Board on Life Sciences

RSO: Friedman, Douglas

Subject/Focus Area: Biology and Life Sciences; Engineering and Technology; Math, Chemistry and Physics

Project Scope
In order to realize the full benefit of research investments intended to enable the advanced manufacturing of chemicals using biological systems, an ad hoc committee will develop a roadmap of necessary advances in basic science and engineering capabilities, including knowledge, tools, and skills.  Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, the committee will identify key technical goals for this next-generation chemical manufacturing, then identify the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. It will also consider the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.  While focused on industrial manufacturing of chemicals, the roadmap challenges identified here will also be relevant to applications in health, energy, environment and agriculture by advancing the tools and techniques required for new development in these areas.

Essential elements of the roadmap that the committee will consider in the study and in its report, include the following:

identification of the core scientific and technical challenges that must be overcome;
 identification of and timeline for tools, measurement techniques, databases, and computational techniques needed to serve as the building blocks for research and applications; how to develop, share, and diffuse common interoperable standards, languages, and measurements; and  when and how to integrate non-technological insights and societal concerns into the pursuit of the technical challenges.  [1]

The report will provide guidance to both the research and research funding communities regarding key challenges, knowledge, tools, and systems needed to advance the science and engineering required for advanced manufacturing of chemicals using biological systems and to develop the workforce required to realize these advances.  The report will not include recommendations related to funding, government organization or policy issues.

[1] These roadmap elements were drawn from a publicly available white paper authored by Richard A. Johnson, Counsel and Senior Partner, Arnold and Porter and used with his permission.

This project is funded by the National Science Foundation and the Department of Energy..

The project began in January 2014 with a report expected in Winter 2015.

Project Duration: 18 months    

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Contact the Public Access Records Office to make an inquiry, request a list of the public access file materials, or obtain a copy of the materials found in the file.

Committee Membership
Committee Membership

 Meeting 1 - 02/26/2014
 Meeting 2 - 03/14/2014
 Meeting 3 - 03/21/2014
 Meeting 4 - 03/28/2014
 Meeting 5 - 04/04/2014
 Meeting 6 - 04/11/2014
 Meeting 7 - 04/18/2014
 Meeting 8 - 04/25/2014
 Meeting 9 - 05/02/2014
 Meeting 10 - 05/16/2014
 Meeting 11 - 05/23/2014
 Meeting 12 - 05/28/2014
 Meeting 13 - 06/06/2014
 Meeting 14 - 06/13/2014
 Meeting 15 - 06/20/2014
 Meeting 16 - 06/27/2014
 Meeting 17 - 07/11/2014
 Meeting 18 - 07/18/2014
 Meeting 19 - 07/25/2014
 Meeting 20 - 08/01/2014
 Meeting 21 - 08/13/2014
 Meeting 22 - 08/22/2014
 Meeting 23 - 08/29/2014
 Meeting 24 - 09/05/2014
 Meeting 25 - 09/09/2014
 Meeting 26 - 09/19/2014
 Meeting 27 - 10/03/2014
 Meeting 28 - 11/03/2014


Reports having no URL can be seen
at the Public Access Records Office
Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals