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Meeting Information



Project Title: Review of EPA's draft paper State of the Science on Nonmonotonic Dose Response

PIN: DELS-BEST-12-06         

Major Unit:
Division on Earth and Life Studies

Sub Unit:
Board on Environmental Studies & Toxicology

RSO:
Martel, Susan

Subject/Focus Area:
Environment and Environmental Studies


Review of EPA's draft paper State of the Science on Nonmonotonic Dose Response
July 23, 2013 - July 24, 2013
National Academy of Sciences Building
2100 C St. NW
Washington D.C.


If you would like to attend the sessions of this meeting that are open
to the public or need more information please contact:


Contact Name: Craig Philip
Email: cphilip@nas.edu
Phone:
Fax:


Agenda:

***Online registration for this meeting is now closed***
The only way to register will be to come to the National Academy of Science building during the public session.

NATIONAL RESEARCH COUNCIL
Committee to Review EPA’s Draft State of the Science Paper on Nonomonotonic Dose Response

July 23, 2013
National Academy of Science Building, Lecture room
2101 Constitution Avenue, NW
Washington, DC

AGENDA

12:45 Registration for Public Session

1:00 Welcome, Introductions, Process for Open Session
David Savitz, Chair
Professor of Epidemiology and Obstetrics and Gynecology,
Brown University


1:10 Introduction and Background
Robert Kavlock, Deputy Assistant Administrator for Science
Office of Research and Development, EPA

Review of EPA’s Draft Report, State of the Science on Nonmonotonic Dose Response
Rita Schoeny, Senior Science Advisor
Office of Science Policy, Office of Research and Development, EPA

2:10 Open Microphone for Public Comment
Each speaker has a maximum time limit of 5 minutes. Accompanying written materials are encouraged.

3:00 Adjourn Public Session


Closed Session Summary Posted After the Meeting

The following committee members were present at the closed sessions of the meeting:
David Savitz (chair)
Andrea Baccarrelli
Robert Chapin
Richard Corley
George Daston
Russ Hauser
Amy Herring
Andreas Kortenkamp
Heather Patisaul (via teleconference)
Elizabeth Pearce
Tracey Woodruff
Lauren Zeise
and Yiliang Zhu.

The following topics were discussed in the closed sessions:
1) Standard NRC discussion of policies, procedures, bias, and conflict of interest.
2) Committee’s statement of task and its approach to its task.
3) Information presented in the open session and submitted to the committee.
4) Development of draft outline.
4) Schedule and objectives for additional meetings.


The following materials (written documents) were made available to the committee in the closed sessions:
1. Letter from Richard A. Becker, ACC, to Eileen Abt, Re: EPA’s June 2013 “Draft State of the Science Evaluation: Nonmonotonic Dose Responses as They Apply to Estrogen, Androgen and Thyroid Pathways and EPA Testing and Assessment Procedures”. Received on July 19, 2013.

2. Comments from Theo Colborn, President, TEDX, The Endocrine Disruption Exchange and Professor Emeritus, University of Florida, Gainesville, to Eileen Abt. Received on July 19, 2013.

3. Comments from Frederick vom Saal, University of Missouri, Columbia, to Eileen Abt. Received on July 21, 2013.

4. Comments from John Peterson Myers, Environmental Health Sciences, to Eileen Abt. Received on July 22, 2013.

5. Comments from Teresa K. Woodruff, The Endocrine Society, to Craig Philip, NRC, Re: Review of EPA's draft paper State of the Science on Nonmonotonic Dose Response PIN: DELS-BEST-12-06. Received on July 22, 2013.

6. Comments from Ana Soto and Carlos Sonnenschein, Tufts School of Medicine, to Craig Philip, NRC. Received on July 22, 2013.

7. Comments from Theo Colborn and Carol Kwiatkowski, The Endocrine Disruption Exchange, to Eileen Abt, RE: Critical Windows of Development. Received July 22, 2013.

8. Comments from Tyrone Hayes, Berkeley, to Eileen Abt, RE: Response to: "State of the Science Evaluation: Nonmonotonic dose responses as they apply to estrogen, androgen, and thyroid pathways and EPA Testing and Assessment Procedures. Received on July 22, 2013.

9. Power Point presentation “State of the Science Evaluation: Nonmonotonic Dose Responses as They Apply to Estrogen, Androgen, and Thyroid Pathways and EPA Testing and Assessment Procedures” given by Bob Kavlock and Rita Schoeny, EPA on July 23, 2013 to the Committee to Review EPA’s Draft Paper, State of the Science on Nonmonotonic Dose Response.

10. Oral public comments made by John Peterson Myers, Environmental Health Sciences, to the Committee to Review EPA’s Draft Paper, State of the Science on Nonmonotonic Dose Response on July 23, 2013. Received July 24, 2013.


Date of posting of Closed Session Summary: August 1, 2013